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Hypericumperforatum L. Showed Antinociceptive Effects Through Opioidergic And Serotonergic Systems

Figure 4: Pre-treatment with intrathecal injection of Naloxane(Nal)5μg /rat on analgesia induced by intraperitoneal injection of 400mg/kg aqueous extract Hpof the first phase of the formalin test.(n=6). Naloxane (Sal-Nal group) significantly produced pain score in comparing Saline-Saline(sal-sal) group(*p<0.05), however Naloxane(Nal-Hp) in comparing Sal-Hpat least +++p<0.001) I nhibited some part of aninociceptive effects of Hp. One-way ANOVA with post-hoc Tukey Test.

Pre-treatment with intrathecal injection of Naloxane(Nal)5μg /rat on analgesia induced by intraperitoneal injection of 400mg/kg aqueous extract Hpof the first phase of the formalin test.(n=6). Naloxane (Sal-Nal group) significantly produced pain score in comparing Saline-Saline(sal-sal) group(*p<0.05), however Naloxane(Nal-Hp) in comparing Sal-Hpat least +++p<0.001) I nhibited some part of aninociceptive effects of Hp. One-way ANOVA with post-hoc Tukey Test.
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