STUDY OF THE GENOTOXIC AND ANTIGENOTOXIC POTENTIAL OF MEDICINAL PLANTS

Abstract

The aim of this research was to investigate the genotoxic and antigenotoxic potential of selected medicinal plants. The study employed a combination of experimental methods to assess the genotoxicity and explore the antigenotoxic effects of these plants. Various assays, including comet assays and micronucleus tests, were utilized to evaluate DNA damage and chromosomal abnormalities in cell lines subjected to plant extracts. The research involved extracting bioactive compounds from the medicinal plants and exposing cells to these extracts to observe potential genotoxic effects. Additionally, the study included co-treatments with known genotoxic agents to assess the antigenotoxic potential of the plant extracts. The methodology aimed to provide a comprehensive understanding of the plants' impact on genetic material and their potential protective effects against genotoxic stress. One notable result of the research was the identification of specific medicinal plants exhibiting significant genoprotective properties. These findings contribute valuable insights into the potential therapeutic applications of these plants in mitigating genetic damage caused by various factors. The study emphasizes the importance of exploring natural sources for potential protective agents against genotoxicity. In conclusion, the research underscores the significance of medicinal plants in the context of genotoxicity and highlights their potential as a source of bioactive compounds with antigenotoxic properties. These findings have implications for both traditional medicine and contemporary pharmacology, providing a basis for further investigations into the development of plant-derived therapeutics with genoprotective potential.

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01 October 2024

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European Publisher

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Gurbanov, R., Dzhambetova, P., & Anokhina, O. (2024). STUDY OF THE GENOTOXIC AND ANTIGENOTOXIC POTENTIAL OF MEDICINAL PLANTS. In M. R. Nakhaev, A. S. Salamova, A. Wojdilo, V. Ricardo, & V. Micale (Eds.), Proofreading - Upcoming Volume: Modern Trends in Governance and Sustainable Development of Socio-economic Systems: From Regional Development to Global Economic Growth, vol -. European Proceedings of Multidisciplinary Sciences (pp. 0-0). European Publisher. https://doi.org/10.15405/epms.2024.09.18